Article: Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression.
Full Text (publisher's website) ;
Article Metadata ;
Article Data (extracted)
Simkin D; Hattori S; Ybarra N; Musial TF; Buss EW; Richter H; Oh MM; Nicholson DA; Disterhoft JF
J. Neurosci., 2015
Table 3.
fAHP and AP half-width evoked synaptically or by direct somatic current injection with control (KMeth) or phrixotoxin in the
internal pipette solution
Group |
1 orthodromic APs |
Somatic current injection ramp |
fAHP (mV) |
AP half-widthVh (ms)
|
fAHP IRAMP (mV)
|
AP half-widththresh (ms)
|
Young-control (n = 43)
|
-57.88 ± 0.32 |
1.15 ± 0.02 |
-50.94 ± 0.63 (42) |
1.16 ± 0.02 |
Young-PaTx (n = 7)
|
-56.79 ± 0.53 |
1.18 ± 0.03 |
|
|
Aged-control (n = 28)
|
-61.68 ± 0.61*** |
0.98 ± 0.02** |
-53.76 ± 0.74 (28)** |
1.09 ± 0.02* |
Aged-PaTx (n = 8)
|
-56.25 ± 0.61 |
1.13 ± 0.02 |
|
|
Inferred neuron-electrophysiology data values